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GSBS Research Topics: PROTEIN DEGRADATION/TRAFFICKING


Chavela M. Carr, Ph.D. * - Piscataway - Structural and functional studies of proteins required for regulation of intracellular membrane fusion. Saccharomyces cerevisiae is used as a model system to study the proteins that control SNARE-mediated vesicle fusion at restricted sites on the plasma membrane.

Monica, A. Driscoll, Ph.D. * - Piscataway - Our lab uses the facile C. elegans model system to investigate molecular and genetic mechanisms of necrotic cell death, aging and mechanical signalling.

David Dubnau, Ph.D. * - Newark - Research concerns regulation of competence and mechanism of DNA transport in Bacillus subtilis.

Member, Public Health Research Institute and Professor, Department of Microbiology and Molecular Genetics. Located in ICPH building, 225 Warren Street, Newark, NJ 07103.

M. Zafri Humayun, Ph.D. * - Newark - We study mechanisms of genetic variability in Escherichia coli and in the pathogen Helicobacter pylori. We have recently defined two novel transient mutator pathways termed UVM and TSM pathways. The TSM pathway reveals unanticipated links among translation, DNA replication and recombination. Antibiotics, helicase.

Hong Li, Ph.D. * - Newark - Center for Advanced Proteomics Research is located in MSB F602 at NJMS. This facility is equipped with state-of-the-art proteomics instruments and bioinformatics systems for protein structure and function analysis. We have a Micromass QTOF mass spectrometer and an ABI 4700 Proteomics Analyzer.

Paul Manowitz, Ph.D. * - Piscataway - Identification of genes predisposing to substance abuse and other human diseases of behavior. This research includes studies of tissue culture and animal models as well as humans to elucidate the genetic, molecular biological,and biochemical bases of these diseases.

Nicola C. Partridge, Ph.D. * - Piscataway - Parathyroid hormone signal transduction pathways regulating transcription of collagenase or stimulating osteoblast cell proliferation. Endocytotic receptors mediating the degradation of secreted collagenase. Mechanisms for enhancing the degradation of collagenase in osteoarthritic chondrocytes.

Natalia Shcherbik, Ph.D. * - Stratford - We currently focus on elucidating the mechanisms of ribosome turnover using Saccharomyces cerevisiae as a model system. We are particularly interested in the role of ubiquitination in controlling the activity of ribonucleases that target ribosomes and how this process in regulated in the cell. Email: shcherna@umdnj.edu

C.K. Suzuki, Ph.D. * - Newark - My lab focuses on the function of molecular chaperones and ATP-dependent proteases in mitochondrial biogenesis and mitochondrial-dependent apoptosis.

* GSBS Faculty Return to Topics list


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