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GSBS Research Topics: ENDOCRINOLOGY/REPRODUCTION


Kevin D. Beck, Ph.D. * - Newark - The program focuses on stress-induced changes in behavior (specifically sensory reactivity and learning/memory). Areas of interest include identifying the neural mechanisms for sex-differences in stress responding and modeling unexplained illness through associative learning of interoceptive stressors.

Rocco V. Carsia, Ph.D. * - Stratford - Research is aimed at elucidating the cellular and molecular events regulating the remodeling of the reptilian adrenal gland. Influences of sex, season and various stressors on reptilian adrencortical cell function are evaluated. A variety of lizard species is used. Email: carsiaro@umdnj.edu

Sylvia Christakos, Ph.D. * - Newark - The Vitamin D Endocrine System:Function and Regulation. Bone.

Laura T. Goldsmith, Ph.D. * - Newark - We are studying signal transduction mechanisms which regulate hormone production from the mammalian ovary and the actions and mechanisms of action of the peptide hormone relaxin.

John Lenard, Ph.D. * - Piscataway - Function of cholesterol in the development and reproduction of the multicellular organism C. elegans. A combination of genetic, biochemical and microscopic techniques are used to understand the processes of hormone biosynthesis, transport and action at a cellular and molecular level.

Barry E. Levin, M.D. * - Newark - How the brain senses, integrates and regulates metabolic systems controlling energy homeostasis in obesity and in diabetes. Emphasis on diet-induced obesity, neural glucosensing, hypoglycemia-induced brain damage. Utilize behavioral, neurochemical, molecular and physiologic techniques.

Joseph Martin, Ph.D. * - Stratford - We study how thyroid hormones (TH) influence the adult mammalian brain through nongenomic mechanisms. THs modulate GABAa receptor binding and protein phosphorylation in nerve terminal fractions without cell nuclei. Currently, temporal patterns of TH release from brain tissue are measured in relation to the subsequent cellular TH response and EEG. Email: jomartin@camden.rutgers.edu

Carlos A. Molina, Ph.D. * - Newark - We are interested in the regulation of gene expression during the cell cycle by the tumor suppressor and transcriptional repressor, Inducible cAMP Early Repressor (ICER). Circadian rhythm.

John, E. Ottenweller, Ph.D. * - Newark - Long-term Effects of Stress on Health and Disease, Multiple Hormone Systems, Physiological Regulation and Behavior. Neuroendocrine Function in Chronic Fatigue Syndrome and Gulf War Syndrome focusing on Adrenal Axis Hormones, but including thyroid hormones and reproductive hormones.

Nicola C. Partridge, Ph.D. * - Piscataway - Parathyroid hormone signal transduction pathways regulating transcription of collagenase or stimulating osteoblast cell proliferation. Endocytotic receptors mediating the degradation of secreted collagenase. Mechanisms for enhancing the degradation of collagenase in osteoarthritic chondrocytes.

Vanessa H. Routh, Ph.D. * - Newark - Central regulation of glucose homeostasis. Electrophysiological and PCR studies of brain slices and isolated neurons in a rodent model of diet-induced obesity and type II diabetes mellitus. Focus on mechanisms by which neurons respond to physiologic changes in extracellular glucose, as well as regulation of glucosensing neurons.

Thresia Thomas, Ph.D. * - Piscataway - Development of therapeutics for breast cancer based on polyamines and estrogens. Molecular mechanism(s) of estrogenic function through the estrogen receptor. Transcriptional regulation of gene expression. Role of environemntal estrogens in breast cancer. Estradiol metabolic pathways

Andrew P. Thomas, Ph.D. * - Newark - 1) Calcium-dependent signal transduction in response to hormones and growth factors, and 2) the effects of cocaine and alcohol on cardiac excitation-contraction coupling. We use digital imaging and laser scanning confocal microscopy to measure calcium and monitor organelle function in living cells; ion channel electrophysiology; molecular biology.

* GSBS Faculty Return to Topics list


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