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GSBS Research Topics: DRUG DEVELOPMENT


Salvatore J. Caradonna, Ph.D. * - Stratford - My laboratory is interested in the post-translational mechanisms that regulate proteins involved in base-excision repair of DNA. We are studying the aberrant pathways that lead to uracil misincorporation into DNA and strategies that may exploit these pathways for cancer drug development. We are also involved in the study of atypical cyclin-like proteins that affect cell-cycle phase transitions. Email: caradonn@umdnj.edu

Lisa Huang, Ph.D. * - Stratford - My current research focuses on the identification of cancer biomarkers in the diagnosis and monitoring of cervical cancer, bladder cancer, and prostate cancer. Another of my research focuses on studying the mechanisms of DNA repair and drug resistance in bladder cancer and prostate cancer. These researches aid to assist in novel drug discovery. Email: lhuang@mdlab.com

Joseph Nickels, Ph.D. * - Stratford - Our research uses proteomic/genomic methods and mouse models to understand the biology of diseases, such as cancer initiation and metastasis, cardiovascular disease, and infectious mycoses. Our goal is discovering novel genes that can be used as biomarkers and drug targets, thus allowing us to diagnose and treat these diseases. Email: jnickels@mdlab.com

Jason Trama, Ph.D. * - Stratford - Our laboratory uses proteomic and genomic data to identify biomarkers for gynecologic and urologic cancers. Our goal is to develop noninvasive methods for diagnosis and monitoring. We also study the mechanisms of tumorigenesis, metastasis and drug resistance in order to identify targets for therapy. Email: jtrama@mdlab.com

Venkat Venkataraman, Ph.D * - Stratford - We are investigating the processes of neuronal transduction in biological clocks and aging with respect to the role of Ca2+ signaling via alpha2 adrenergic receptors and membrane guanylate cyclases. Email: venkatar@umdnj.edu

John-Paul Vermitsky, Ph.D. * - Stratford - Our research uses proteomic and genomic methods to understand the mechanisms of antifungal drug resistance in a variety of Candida species. Our goal is discovering new markers to detect resistance and potential drug targets which will be used in our high-through put screens. Email: jvermitsky@mdlab.com.

* GSBS Faculty Return to Topics list


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